Figure 4 | Scientific Reports

Figure 4

From: Direct thrombin inhibitors as alternatives to heparin to preserve lung growth and function in a murine model of compensatory lung growth

Figure 4

Immunohistochemistry. Representative micrographs at 200 × magnification of co-stained lung tissue for the endothelial cell marker CD31 (green) and nuclear marker DAPI (blue) at postoperative day 8 following left pneumonectomy (A). Based on quantification, CD31 was decreased in heparin-treated mice compared to controls (B). There was no significant difference in CD31 staining in the bivalirudin or argatroban groups. Statistical analysis of the experimental groups was done using analysis of variance (ANOVA), with Dunnett’s adjustment for multiple comparisons. Shown are mean ± standard error. *P < 0.05.

Back to article page