Figure 1 | Scientific Reports

Figure 1

From: The telomerase activator TA-65 protects from cigarette smoke-induced small airway remodeling in mice through extra-telomeric effects

Figure 1

TA-65 effects on cigarette smoke-induced small airway remodeling. Representative lung tissue sections of mice exposed to air or cigarette-smoke (CS) with or without TA-65, and stained for HE, picrosirius red, α-SMA, PAS, Collagen I, Collagen III, or Vimentin (a). Quantification of small airways wall thickness by manual [(b), in mean] or automated method [(c), distribution], α-SMA expression (d), PAS staining (e), Collagen I (f), Collagen III (g) and Vimentin (h) expression. Original magnification, ×20. n = 7–8 mice per group. Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001.

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