Table 2 Ventilatory mechanics and gas analysis.

From: Driving pressure-guided ventilation improves homogeneity in lung gas distribution for gynecological laparoscopy: a randomized controlled trial

Characteristics

Control

Titration

p

(n = 24)

(n = 24)

Time

Group

Inter

Compliance (mL cmH2O1)

  

 < 0.001

0.02

 < 0.001

immediately after intubation

62.5(10.4)

60.8(9.3)

   

10 min after PNP

32.3(6.6)

29.3(5.4)

   

1 h after PNP

29.4(6.1)

36.7(8.3)**

   

10 min after deflation of PNP

43.0(11.8)

52.5(11.1)*

   

end of surgery

44.1(10.7)

55.1(10.3)**

   

Ppeak (cmH2O)

  

 < 0.001

0.08

 < 0.001

immediately after intubation

14(3.9)

14.5(2.6)

   

10 min after PNP

21.5(3.8)

22.1(2.6)

   

1 h after PNP

23(4.6)

26.3(2.5)*

   

10 min after deflation of PNP

17.7(3.1)

20.5(3.5)*

   

end of surgery

17.8(3.2)

17.1(3.8)

   

Pplat (cmH2O)

  

 < 0.001

0.06

0.01

immediately after intubation

11.5(4.1)

12.2(2.8)

   

10 min after PNP

19.5(4.0)

20.0(3.0)

   

1 h after PNP

21.5(4.0)

24.5(2.1)*

   

10 min after deflation of PNP

15.2(3.2)

17.9(3.7)*

   

end of surgery

14.9(2.8)

14.9(3.7)

   

PaCO2

  

 < 0.001

0.89

0.39

immediately after intubation

35.9(4.1)

34.0(4.1)

   

1 h after PNP

41.9(4.0)

41.9(5.5)

   

immediately after extubation

45.0(7.2)

46.3(6.0)

   

1 h after extubation

39.4(4.3)

40.1(4.5)

   

pH

  

 < 0.001

0.05

0.33

immediately after intubation

7.41(0.028)

7.43(0.039)

   

1 h after PNP

7.34(0.042)

7.36(0.047)

   

immediately after extubation

7.32(0.045)

7.32(0.046)

   

1 h after extubation

7.35(0.039)

7.36(0.045)

   
  1. Values are the mean (SD) or number (%). Values are the mean (SD). Ppeak airway peak pressure; Pplat airway plateau pressure; PNP pneumoperitoneum. *p < 0.05; **p < 0.01 compared to the control group.