Figure 3 | Scientific Reports

Figure 3

From: Region of interest-specific loss functions improve T2 quantification with ultrafast T2 mapping MRI sequences in knee, hip and lumbar spine

Figure 3

T2 quantification performance of optimal ROI-specific pipeline in knee cartilage. (a) Visual pipeline performance within the knee for a representative patient, with corresponding NRMSEs for cartilage in the predicted T2 map slice. Performance remains strong through R = 10, maintaining T2 patterns in the medial tibiofemoral cartilage, indicating pipeline utility. Predicted maps generated by the network are masked using a cartilage segmentation mask and superimposed on the ground truth, fully sampled TE = 0 ms MAPSS echo time image. (b) Bland–Altman plots for all scans within test set for which multiclass cartilage compartment segmentations were available (n = 16, 6 cartilage compartments for each). Predicted T2 values demonstrate minimal bias and tight limits of agreement across most tested R, with best performance coming from patellofemoral cartilage.

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