Figure 5
From: Identification of key immune-related genes in dilated cardiomyopathy using bioinformatics analysis
Construction of PPI network and identification of the hub genes in DCM. (A) PPI network of DEGs was constructed using STRING; A total of three algorithms from CytoHubba, including (B) Degree algorithm, (C) MCC algorithm, and (D) MNC algorithm, were used for the top ten genes; (E) The key module within the PPI network was identified from MCODE; (F) The hub genes were identified via the Upset plot. PPI: protein–protein interaction; DEGs: differentially expressed genes; MCC: maximal clique centrality; MNC: maximum neighborhood component. Red color represents up-regulated genes and green color represents down-regulated genes in (A) and (E); Advanced ranking is represented by a redder color in (B–D).
