Figure 2 | Scientific Reports

Figure 2

From: Association of LncRNA-PAX8-AS1 and LAIR-2 polymorphisms along with their expression with clinical and subclinical hypothyroidism

Figure 2

Influence of studied SNPs on the gene expression of LncRNA-PAX8-AS1, LAIR-2 mRNA and protein in hypothyroidism patients. (A, B) Fold change of serum expression levels of LncRNA-PAX8-AS1 in different LncRNA-PAX8-AS1 rs4848320 genotypes (CC, n = 30, CT, n = 56, TT, n = 14) and rs1110839 genotypes (GG, n = 22, GT, n = 57, TT, n = 21) in clinical hypothyroidism patients, respectively. (C, D) Fold change of serum expression of LAIR-2 mRNA, (E, F) Serum LAIR-2 protein concentrations in different LAIR-2 rs2287828 genotypes in clinical hypothyroidism (CC, n = 30, CT, n = 54, TT, n = 16) and subclinical hypothyroidism (CC, n = 47, CT, n = 47, TT, n = 16) patients, respectively. Data are expressed as box blot; the box represents the 25–75% percentiles; the line inside the box represents the median and the upper and lower lines representing the 10–90% percentiles. P < 0.05 means statistical significance.

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