Table 6 Logistic regression analysis to predict the risk of clinical hypothyroidism.

From: Association of LncRNA-PAX8-AS1 and LAIR-2 polymorphisms along with their expression with clinical and subclinical hypothyroidism

Parameter

β-coefficient

SE

Pa value

ORa

OR (95% CI)

Univariate analysis

LncRNA-PAX8-AS1

 − 4.126

0.475

 < 0.0001

0.016

0.006–0.041

LAIR-2 mRNA

0.101

0.017

 < 0.0001

1.110

1.107–1.114

LAI-2 protein

0.053

0.060

0.379

1.055

0.937–1.187

Multivariate analysis

LncRNA-PAX8-AS1

 − 3.646

0.531

 < 0.0001

0.026

0.009–0.074

LAIR-2 mRNA

0.074

0.015

 < 0.0001

1.076

1.044–1.110

Constant

0.970

    
  1. Clinical hypothyroidism (n = 100) versus healthy control + subclinical hypothyroid group (n = 205). Log likelihood of the stepwise multivariate logistic regression model =  − 107.847, − 2 Log likelihood = 215.694, P < 0.0001. P values in bold means statistical significance between groups, P < 0.05.a adjusted for age and sex.
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