Figure 5 | Scientific Reports

Figure 5

From: The interrelationships between neuronal viability, synaptic integrity, microglial responses, and amyloid-beta formation in an in vitro neurotrauma model

Figure 5

CD206+ microglia predominate during coculture with injured neurons, whereas CD16/32+ microglia predominate during stretch injury. Representative flow cytometry plots are shown (left panels). Quantification of the percentages of CD16/32+ microglia and CD206+ microglia is presented (right panels). Each bar represents the mean ± SD of 6 independent samples per experimental condition. (A) There was a significant main effect for group [F(2,30) = 37.45, P < 0.0001], for phenotype [F(1,30) = 274.1, P < 0.0001], and for interaction [F(2,30) = 47.61, P < 0.0001]. (B) There was a significant main effect for group [F(3,40) = 68.77, P < 0.0001], for phenotype [F(1,40) = 630.7, P < 0.0001], and for interaction [F(3,40) = 71.38, P < 0.0001]. Two-way ANOVA with Tukey’s test was used for multiple comparisons.

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