Figure 4

Effect of thrombomodulin on thrombogenicity of SEVs and LEVs. Mean TG curves for healthy donor and COVID-19 (+) SEVs (A), and LEVs (D) with and without thrombomodulin. Peak height and velocity values of healthy donor and COVID-19 (+) patients SEVs (B,C) and LEVs (E,F) respectively with and without thrombomodulin antibody. 100 µg/mL of SEVs and LEVs were used for these experiments. healthy SEVs (n = 13) LEVs (n = 14), COVID-19 (+) SEVs (n = 12) and LEVs (n = 14). Datapoints indicate individual measurements, and p-values are from the one-way ANOVA analysis for comparison between groups. ns, p > 0.05; *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; ****p ≤ 0.0001.