Table 4 Model reaction to assess CYP-activity.
From: Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism
Model reaction | CYP enzymes | Measured metabolite |
|---|---|---|
Midazolam | CYP3A4 | OH-Midazolam |
Caffeine | CYP1A2 | No metabolites |
Codeine | CYP2D6 | Norcodeine, codeine-6-glucuronide, morphine-3-glucuronide, morphine |
