Table 1 Patient characteristics at ICU admission.

From: Elevated endothelial dysfunction-related biomarker levels indicate the severity and predict sepsis incidence

Categories

Infection (n = 28)

Septic non-shock (n = 31)

Septic shock (n = 46)

P value

Age (years, mean ± SD)

62 ± 18

59 ± 18

62 ± 17

0.768

Gender (male, %)

64.29

77.42

63.04

0.591

APACHEII score

15 (11–16)

16 (14–19)

17 (15–19)*

0.013

SOFA score

0 (0–2)

5 (4–8)*

11 (9–14)*#

0.000

HR (bpm)

96 ± 24

106 ± 20

110 ± 22*

0.031

MAP (mmHg)

89 ± 12

91 ± 16

84 ± 15

0.070

CVP (mmHg)

–

11 ± 7

8 ± 4

0.327

Pv-aCO2 (mmHg)

–

4 (1.7–6.9)

5.1 (2.7–6.1)

0.453

ScvO2 (%)

–

77.3 ± 9.3

75.2 ± 10.3

0.716

Lactate (mmol/l)

1.0 (0.8–1.6)

1.6 (1.1–2.3)

4.0 (2.2–7.8)*#

0.000

  1. Data was presented by mean standard deviation, n (%), or median (interquartile range). For normally distributed data, comparisons among multiple groups were conducted by one-way analysis of variance, and those between two groups were carried out with the Least Significant Difference (LSD) post hoc test.
  2. For data without normal distribution, Post hoc tests and between-group analyses were performed by Mann–Whitney nonparametric tests and Bonferroni corrected.
  3. APACHE Acute Physiology and Chronic Health Evaluation, SOFA sequential organ failure assessment score, HR heart rate, MAP mean arterial blood pressure, CVP central venous pressure, Pv-aCO2 venous-to-arterial carbon dioxide difference (Pv-aCO2), ScvO2 central venous blood oxygen saturation.
  4. *P < 0.05 for the comparison between infection and septic non-shock, between infection and septic shock.
  5. #P < 0.05 for the comparison between septic non-shock and septic shock.
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