Table 3 Risk factor analysis of Recurrence of Infection.

From: Outcome of multi-staged induced membrane technique based on post-debridement cultures for the management of critical-sized bone defect following fracture-related infection

Variables

Univariate cox regression

Multivariate cox regression

HR (95% CI)

p value

HR (95% CI)

p value

Type of soft tissue

2.113 (0.986–4.531)

0.0445

1.537 (0.629–3.757)

0.345

Number of stages before BG

1.437 (1.116–1.85)

0.005

1.083 (0.845–1.387)

0.5284

Infected previous free flap

2.38 (1.19–4.761)

0.0142

3.14 (1.393–7.077)

0.0058*

Surprise culture positive

4.736 (2.359–9.507)

0.0001

3.608 (1.733–7.514)

0.0006*

Deviation of protocol

3.341 (1.703–6.553)

0.0004

2.585 (1.295–5.163)

0.0071*

Elevated ESR before BG

2.525 (1.142–5.581)

0.0221

2.24 (1.007–4.98)

0.0479*

  1. *Significant at p value < 0.05.
  2. BG: bone grafting.
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