Figure 2

Immune cluster characterization and cell abundance. (A) Relative expression of 17 immune cell abundance stacked column charts in each sample estimated using CIBERSORT. (B) Immune cluster characterization heatmap using ssGSEA (‘GSVA’ package). (C) Immune cell abundance histogram of all included samples estimated using CIBERSORT. (D) Immune cell abundance histogram of different groups estimated using CIBERSORT. (E) Stromal score of three different groups using ESTIMATE. (F) Immune score of three different groups using ESTIMATE. (G) ESTIMATE score of three different groups using ESTIMATE. Data are presented as the mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001.