Table 1 Patient characteristics for antibiotic prescription and outcomes among outpatients or inpatients.

From: Prevalence and characteristics of antibiotic prescription for acute COVID-19 patients in Japan

Characteristic

Antibiotics prescribed (n = 7741)

Not prescribed (n = 65,786)

Adjusted odds ratio (95% CI)* for antibiotic prescription

A: Outpatients with acute COVID-19 between Jan 2020 and Nov 2021 in Japan (N = 73,527)

Older patients, n (%)

4271 (55.17%)

9079 (13.80%)

4.66 (4.41, 4.93)

Male, n (%)

4308 (55.65%)

35,667 (54.22%)

1.02 (0.97, 1.08)

Charlson index, mean (SD)

3.09 (3.51)

0.71 (1.82)

1.22 (1.21, 1.23) ***

Characteristic/outcome

Antibiotics prescribed (n = 10,809)

Not prescribed (n = 56,103)

Adjusted odds ratio (95% CI)** for antibiotic prescription

B: Inpatients with acute COVID-19 between Jan 2020 and Nov 2021 in Japan (N = 66,912)

Older patients, n (%)

5885 (54.45%)

16,375 (29.19%)

2.10 (2.01, 2.21)

Male, n (%)

6690 (61.89%)

31,758 (56.61%)

1.12 (1.07, 1.18)

Charlson index, mean (SD)

3.59 (3.11)

2.34 (2.81)

1.06 (1.05, 1.07)***

Oxygen therapy, n (%)

6596 (61.02)

15,073 (26.87)

3.44 (3.28, 3.60)

Invasive mechanical ventilation, n (%)

1674 (15.49)

564 (1.01)

15.09 (13.60, 16.74)

In-hospital mortality, n (%)

1332/10,809 (12.33%)

1058/56,103 (1.89%)

N/A

Hospital stay, mean days (SD)

17.42 (0.17)

10.79 (0.04)

N/A

  1. SD standard deviation, CI confidence interval.
  2. *Adjusted for older patients, male, Charlson index.
  3. **Adjusted for older patients, male, Charlson index, requiring oxygen therapy, and requiring invasive mechanical ventilation. Odds ratios for antibiotic prescription are not estimated for in-hospital mortality and hospital stay, because these outcomes are not considered as predictors for antibiotic prescription.
  4. ***Odds ratio by one point increase of the index score.