Table 1 Characteristics of patients diagnosed with cancer after ischemic stroke.
From: A risk model for prediction of diagnosis of cancer after ischemic stroke
Cancer diagnosed within 1 year after stroke: 34 patients | Cancer diagnosed within 3 years after stroke: 55 patients | |
|---|---|---|
Median time from stroke to cancer diagnosis: months, 95% CI | 0.5 (0.2–4.8) | 7.3 (1.5–12.9) |
Diagnosis of cancer during hospitalization for ischemic stroke: n (%) | 20 (58.8%) | 20 (36.4%) |
Diagnostic pathways leading cancer diagnosis during hospitalization for stroke: | ||
(1) Cancer as incidental finding without prior suspicion of cancer: n (%) | 3/20 (15%) | 3/20 (15%) |
(2) Targeted diagnostics done due to symptoms or laboratory findings prompting suspicion for cancer: n (%) | 12/20 (60%) | 12/20 (60%) |
(3) CT scan of chest and abdomen or whole body fluorodeoxyglucose positron emission tomography for differential diagnosis of cancer | 5/20 (25%) | 5/20 (25%) |
Type of cancer (first diagnosis after stroke) n (%) | ||
Lung cancer | 6 (17.6%) | 8 (14.5%) |
Lymphoma and hematologic diseases | 6 (17.6%) | 8 (14.5%) |
Prostate cancer | 3 (8.8%) | 5 (9.1%) |
Head and neck cancer | 2 (5.9%) | 4 (7.3%) |
Cancer of unknown origin | 3 (8.8%) | 3 (5.5%) |
Breast cancer | 2 (5.9%) | 3 (5.5%) |
Pancreatic cancer | 2 (5.9%) | 3 (5.5%) |
Colorectal cancer | 2 (5.9%) | 3 (5.5%) |
Skin cancer | 2 (5.9%) | 2 (3.6%) |
Urothelial cancer | 1 (2.9%) | 6 (10.9%) |
Kidney cancer | 1 (2.9%) | 2 (3.6%) |
Sarcoma | 1 (2.9%) | 2 (3.6%) |
Gastric cancer | 1 (2.9%) | 1 (1.8%) |
Central nervous system | 1 (2.9%) | 1 (1.8%) |
Biliary tract cancer | 1 (2.9%) | 1 (1.8%) |
Ovarian cancer | – | 1 (1.8%) |
Second cancer after stroke | 3 (8.8%) | 6 (10.9%) |
Ovarian cancer | 1 (2.9%) | 1 (1.8%) |
Lymphoma and hematologic diseases | 1 (2.9%) | 2 (3.6%) |
Urothelial cancer | 1 (2.9%) | 1 (1.8%) |
Lung cancer | 1 (1.8%) | |
Prostate cancer | 1 (1.8%) | |
Lymph node metastasis: n (%) | ||
Yes | 13 (38.2%) | 17 (30.9%) |
No | 8 (23.5%) | 18 (32.7%) |
No data | 13 (38.2%) | 20 (36.4%) |
Distant metastasis: n (%) | ||
Yes | 13 (38.2%) | 16 (29.1%) |
No | 11 (32.4%) | 24 (42.6%) |
No data | 10 (29.4%) | 15 (27.3%) |
Any tumor-related therapeutic intervention including surgery or systemic therapy or radiotherapy after stroke: n (%) | ||
Yes | 15 (44.1%) | 27 (49.1%) |
Systemic therapy | 9 (26.5%) | 13 (23.6%) |
Radiotherapy | 4 (11.8%) | 4 (7.3%) |
No | 8 (23.5%) | 10 (18.2%) |
No data | 11 (32.4%) | 18 (32.7%) |