Table 3 Risk of cancer diagnosis after stroke without and with consideration of death as competing risk in multivariable analyses.
From: A risk model for prediction of diagnosis of cancer after ischemic stroke
Risk of cancer diagnosis within 1 year after stroke Data for 651 patients with all covariables available | Risk of cancer diagnosis within 3 years after stroke Data for 651 patients with all covariables available | |||||||
|---|---|---|---|---|---|---|---|---|
Hazard ratio (95% CI) | p value | Subdistribution hazard ratio (95% CI) | p value | Hazard ratio (95% CI) | p value | Subdistribution hazard ratio (95% CI) | p value | |
Sex Male versus female (ref) | 1.94 (0.72–5.19) | 0.19 | 2.0 (0.67–5.99) | 0.22 | 1.24 (0.60–2.62) | 0.56 | 1.28 (0.56–2.93) | 0.56 |
Age | 1.04 (1.0–1.09) | 0.07 | 1.03 (0.99–1.08) | 0.11 | 1.04 (1.00–1.07) | *0.026 | 1.03 (1.0–1.05) | 0.07 |
White blood cell count > 9,600/µl versus ≤ 9,600/µl (ref) | 3.96 (1.46–10.77) | *0.007 | 3.68 (1.30–10.40) | *0.014 | 2.56 (1.21–5.41) | *0.044 | 2.45 (1.18–5.07) | *0.016 |
Platelet count > 400,000/µl versus ≤ 400,000/µl (ref) | 7.86 (2.28–27.10) | *0.001 | 7.71 (2.44–24.41) | *0.001 | 4.11 (1.36–12.39) | *0.012 | 3.95 (1.39–11.27) | *0.01 |
Hemoglobin < 117 g/l (for women) and < 134 g/l (for men) versus > 117 g/l (for women) and for > 134 g/l (men) (ref) | 1.57 (0.59–4.12) | 0.36 | 1.47 (0.56–3.85) | 0.43 | 1.49 (0.67–3.34) | 0.33 | 1.29 (0.59–2.82) | 0.53 |
Lactate dehydrogenase > 480 U/l versus ≤ 480 U/l (ref) | 1.42 (0.52–3.89) | 0.39 | 1.63 (0.64–4.19) | 0.31 | 1.18 (0.52–2.71) | 0.69 | 1.28 (0.54–3.03) | 0.57 |
D-dimers ≥ 3 mg/l versus < 3 mg/l (ref) | 4.40 (1.48–13.13) | *0.008 | 3.67 (1.42–9.50) | *0.007 | 2.54 (1.05–6.17) | *0.039 | 2.13 (0.97–4.68) | 0.06 |
Venous thromboembolism prior to stroke Yes versus no (ref) | 2.46 (0.78–8.36) | 0.12 | 2.78 (0.99–7.82) | 0.05 | 1.59 (0.53–4.75) | 0.40 | 1.76 (0.61–5.05) | 0.30 |
Ischemic lesions in ≥ 2 vascular territories not attributed to cardioembolic etiology (TOAST 2) Yes versus no (ref) | 2.70 (0.81–8.98) | 0.10 | 2.51 (0.79–7.98) | 0.12 | 1.63 (0.55–4.86) | 0.38 | 1.51 (0.51–4.48) | 0.46 |
