Table 1 Clinical characteristics of patients with PIMS-all, PIMS-non-KD, PIMS-KD and KD.

From: A comparison of pediatric inflammatory multisystem syndrome temporarily-associated with SARS-CoV-2 and Kawasaki disease

 

PIMS-all (n = 395)

PIMS-non-KD (n = 153)

PIMS-KD (n = 242)

p-valuea

KD

p-valueb

(95% CI)

(n = 69)

(95% CI)

Age, median in years (IQR)

7 (4–11)

9 (5–13)

7 (4–10)

 < 0.001 (n.d.)

3 (1–4)

 < 0.001 (n.d.)

< 1 y, n (%)

13 (3.3)

5 (3.3)

8 (3.3)

13 (18.8)

1–6 y, n (%)

156 (39.5)

47 (30.7)

109 (45.0)

45 (65.2)

7–15 y, n (%)

199 (50.4)

80 (52.3)

119 (49.2)

11 (15.9)

16–19 y, n (%)

27 (6.8)

21 (13.7)

6 (2.5)

0

Sex

Female, n (%)

141 (35.7)

55 (35.9)

86 (35.5)

1.000 (n.d.)

26 (37.7)

0.786 (n.d.)

Male, n (%)

254 (64.3)

98 (64.1)

156 (64.5)

43 (62.3)

Male-to-female ratio

1:08

1:08

1:08

1:07

Ethnicity

Caucasian, n (%)

226 (57.2)

89 (58.2)

137 (56.6)

0.631 (n.d.)

47 (68.1)

0.025 (n.d.)

African, n (%)

26 (6.6)

9 (5.9)

17 (7.0)

2 (2.9)

Arabic, n (%)

64 (16.2)

25 (16.3)

39 (16.1)

6 (8.7)

Asian, n (%)

18 (4.6)

4 (2.6)

14 (5.8)

8 (11.6)

Other, n (%)

61 (15.4)

26 (17.0)

35 (14.5)

6 (8.7)

Concomitant diseases

94 (23.8)

44 (28.8)

50 (20.7)

0.430 (− 10.2 to 4.4)

15 (21.7)

0.440 (− 13.0 to 5.7)

Respiratory, n (%)

18 (4.6)

7 (4.6)

11 (4.5)

0.990 (− 4.3 to 4.2)

1 (1.4)

0.230 (− 2.0 to 8.2)

Cardiovascular, n (%)

13 (3.3)

4 (2.6)

9 (3.7)

0.550 (− 2.5 to 4.7)

3 (4.3)

0.660 (− 5.7 to 3.6)

Gastrointestinal, n (%)

9 (2.3)

4 (2.6)

5 (2.1)

0.720 (− 3.6 to 2.5)

0

0.210 (− 1.3 to 5.8)

Hepatic, n (%)

2 (0.5)

2 (1.3)

0

0.070 (− 2.7 to 0.1)

0

0.550 (− 1.2 to 2.2)

Renal, n (%)

4 (1.0)

2 (1.3)

2 (0.8)

0.640 (− 2.5 to 1.6)

2 (2.9)

0.200 (− 4.8 to 1.0)

Neurological, n (%)

7 (1.8)

4 (2.6)

3 (1.2)

0.310 (− 4.1 to 1.3)

1 (1.4)

0.850 (− 3.0 to 3.7)

Psychiatric, n (%)

4 (1.0)

2 (1.3)

2 (0.8)

0.640 (− 2.5 to 1.6)

0

0.400 (− 1.4 to 3.4)

Hematological, n (%)

8 (2.0)

4 (2.6)

4 (1.7)

0.510 (− 3.8 to 1.9)

1 (1.4)

0.750 (− 3.0 to 4.1)

Oncological, n (%)

1 (0.3)

0

1 (0.4)

0.430 (− 0.6 to 1.4)

0

0.680 (− 0.9 to 1.4)

Organ/Bone marrow transplant, n (%)

1 (0.3)

1 (0.7)

0

0.210 (− 1.7 to 0.4)

0

0.680 (− 0.9 to 1.4)

Autoimmune, n (%)

8 (2.0)

4 (2.6)

4 (1.7)

0.510 (− 3.8 to 1.9)

3 (4.3)

0.240 (− 6.2 to 1.6)

Immunodeficiency, n (%)

1 (0.3)

1 (0.7)

0

0.210 (− 1.7 to 0.4)

0

0.680 (− 0.9 to 1.4)

Immunosuppressive drug, n (%)

2 (0.5)

1 (0.7)

1 (0.4)

0.740 (− 1.7 to 1.2)

0

0.550 (− 1.2 to 2.2)

Others, n (%)

16 (4.1)

8 (5.2)

8 (3.3)

0.350 (− 5.9 to 2.1)

4 (5.8)

0.510 (− 7.0 to 3.5)

  1. PIMS, pediatric multisystem inflammatory syndrome; KD, Kawasaki disease. acomparison between PIMS-non-KD and PIMS-KD. bcomparison between PIMS-all and KD; 95% CI, 95%-confidence interval; n; number of cases; IQR, interquartile range; y, years; n.d.; not determined. P values in bold are considered statistically significant.
Back to article page