Figure 5 | Scientific Reports

Figure 5

From: Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity

Figure 5

Replication analysis in TEDS. (a) Pearson correlations of E-factors with subject-specific school grades; (b) Genetic correlations of TEDS E-factors with iPSYCH E-factors estimated using bivariate LD score regression; (c) Associations of polygenic scores for E1, E2, E3 and E4 (based on iPSYCH SNP weights) with E1 and E2 in TEDS tested using linear regression; standardized effect sizes (beta) and standard errors are shown; (d) Associations of polygenic scores for the six psychiatric disorders with E1 and E2 in TED; standardized effect sizes (beta) and standard errors are shown. SCZ schizophrenia, BD bipolar disorder, MDD major depressive disorder, ADHD attention deficit hyperactivity disorder, ASD autism spectrum disorder, AN anorexia nervosa. Star symbols indicate statistical significance after multiple testing corrections (P < 0.006 for panel c and P < 0.004 for d).

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