Figure 1 | Scientific Reports

Figure 1

From: Preclinical evaluation of pentagamavunone-1 as monotherapy and combination therapy for pancreatic cancer in multiple xenograft models

Figure 1

PGV-1 suppresses pancreatic cancer cell proliferation in vitro. MIA PaCa-2 (a) and PANC-1 (b) cells were cultured with PGV-1 (0.4 μM), gemcitabine (0.10 and 0.15 μM), and a combination of PGV-1 (0.4 μM) and gemcitabine (0.10 and 0.15 μM) for 3 days. Viable cells were counted by the trypan blue exclusion method at the indicated time. P values were calculated with Student’s t test. The results are shown as the average of 4 independent experiments (means ± SEM). (c) MIA PaCa-2 and PANC-1cells (1 × 107 cells) were subcutaneously injected into nude mice, and tumor volumes were measured every 2 days. The results are shown as the average of 4 independent experiments (one mouse per one independent experiment. means ± SEM).

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