Table 3 Selected SNPs used for studying thermotolerance adaptation genes in various sheep breeds.
SNP | Locus | Gene name | Allele substitution | Chromosome | |
|---|---|---|---|---|---|
1 | rs593507294 | LEP | Leptin | C/T | 4 |
2 | rs161110765 | SOCS3 | Suppressor of cytokine signalling 3 | A/C | 11 |
3 | rs161286575 | PPARG | Peroxisome proliferator-activated receptor gamma | C/T | 19 |
4 | rs603870279 | ASIP | Agouti signalling protein | C/T | 13 |
5 | rs598380853 | ASIP | Agouti signalling protein | C/G | 13 |
6 | rs601650611 | ASIP | Agouti signalling protein | C/G | 13 |
7 | rs420959261 | CSN1S1 | Casein alpha s1 | C/T | 6 |
8 | rs587905107 | CSN1S1 | Casein alpha s1 | C/T | 6 |
9 | rs416941267 | CSN2 | Casein beta | G/T | 6 |
10 | rs430298704 | CSN2 | Casein beta | C/T | 6 |
11 | rs420611298 | ABCG1 | ATP binding cassette subfamily G member 1 | G/T | 1 |
12 | rs159956881 | ABCG2 | ATP binding cassette subfamily G member 1 | A/G | 6 |
13 | rs159876394 | IGF1 | Insulin like growth factor 1 | C/G | 3 |
14 | rs160257833 | ESR1 | Oestrogen receptor 1 | A/G | 8 |
15 | rs591182158 | ESR1 | Oestrogen receptor 1 | A/G | 8 |
16 | rs598908205 | GNRH1 | Gonadotropin releasing hormone 1 | C/T | 2 |
17 | rs411181557 | DIO2 | Deiodinase iodothyronine type II | C/G | 7 |
18 | rs414917134 | BTNL2 | Butyrophilin like 2 | C/G | 20 |
19 | rs405270595 | BTN1A1 | Butyrophilin | A/G | 20 |
20 | rs161146164 | GHR | Growth hormone receptor | G/T | 16 |
21 | rs55631463 | GHR | Growth hormone receptor | A/G | 16 |
22 | rs407318935 | STAT1 | Signal transducer and activator of transcription 1 | A/G | 2 |
23 | rs161691559 | HSP90AB1 | Heat shock protein 90 alpha family class B member 1 | A/G | 20 |
24 | rs397514115 | HSP90AA1 | Heat shock protein 90 alpha family class A member 1 | G/C | 18 |
25 | rs397514116 | HSP90AA1 | Heat shock protein 90 alpha family class A member 1 | C/G | 18 |
26 | rs397514117 | HSP90AA1 | Heat shock protein 90 alpha family class A member 1 | A/C | 18 |
27 | rs397514269 | HSP90AA1 | Heat shock protein 90 alpha family class A member 1 | A/G | 18 |
28 | rs397514270 | HSP90AA1 | Heat shock protein 90 alpha family class A member 1 | G/T | 18 |
29 | rs397514271 | HSP90AA1 | Heat shock protein 90 alpha family class A member 1 | A/G | 18 |
30 | rs397514268 | HSP90AA1 | Heat shock protein 90 alpha family class A member 1 | -/G | 18 |
31 | rs397514272 | HSP90AA1 | Heat shock protein 90 alpha family class A member 1 | G/T | 18 |
32 | rs397514273 | HSP90AA1 | Heat shock protein 90 alpha family class A member 1 | A/G | 18 |
33 | rs588145625 | HSPA8 | Heat shock protein family A member 8 | A/G | 15 |
34 | rs161504783 | HSPA12A | Heat shock protein family A member 12A | C/T | 22 |
35 | rs160077209 | HSPA4 | Heat shock protein family A member 4 | A/G | 5 |
36 | rs589164764 | IL1R1 | Interleukin 1 receptor type 1 | C/T | 3 |
37 | rs160387232 | IL1R1 | Interleukin 1 receptor type 1 | C/T | 3 |
38 | rs590620426 | IL2 | Interleukin 2 | C/G | 17 |
39 | rs596312311 | IL2 | Interleukin 2 | C/T | 17 |
40 | rs416425182 | TR | Thyroglobulin | A/C | 9 |
41 | rs595200178 | TR | Thyroglobulin | A/G | 9 |
42 | rs418400798 | TR | Thyroglobulin | C/T | 9 |
43 | rs410259751 | IL33 | Interleukin 33 | G/T | 2 |
44 | rs162295351 | HSP90AB1 | Heat shock protein 90 alpha family class B member 1 | A/C | 20 |
45 | rs161691552 | HSP90AB1 | Heat shock protein 90 alpha family class B member 1 | A/G | 20 |
46 | rs597293577 | STAT_PIAS3 | Protein inhibitor of activated STAT, 3 | C/T | 1 |
47 | rs593155540 | STAT_PIAS3 | Protein inhibitor of activated STAT, 3 | A/G | 1 |
48 | rs602521720 | HCRT | Hypocretin neuropeptide precursor | C/G | 11 |
49 | rs425706327 | USP19 | Ubiquitin specific peptidase 19 | A/G | 19 |
50 | rs161274296 | USP19 | Ubiquitin specific peptidase 19 | G/T | 19 |
51 | rs588498137 | STAT3 | Signal transducer and activator of transcription 3 | A/G | 11 |
