Table 4 Performance of the two Risk Prediction Models in the Research Cohort.

From: A preoperative magnetic resonance imaging-based model to predict biochemical failure after radical prostatectomy

Performance parameter

Risk threshold, %

Model

Comparison

Baseline

MRI

MRI vs baseline

AUC (95% Cl)

TPR, % (95% Cl)

NA

78 (62–85)

86 (75–94)

8 (1 to 32)a

10

99 (85–98)

85 (78–96)

-14 (-20 to 11)

15

84 (78–98)

80 (72–96)

-4 (-9 to 1)

20

86 (74–98)

81 (61–90)

-5 (-10 to 2)

FPR, % (95% Cl)

10

74 (28–94)

52 (14–60)

-22 (-39 to -8)

15

58 (23–83)

41 (11–44)

-17 (-25 to 4)

20

44 (14–62)

32 (10–40)

-12 (-29 to -1)

NB, % (95% Cl)

10

15 (11–24)

24 (13–34)

9 (-2 to 13)

15

20 (13–32)

25 (15–36)

5 (-8 to 20)

20

18 (9–30)

20 (12–32)

2 (0 to 5)

NRFP, % (95% Cl)

10

7 (0–12)

-1 (-4–8)

-8 (-14 to 3)

15

13 (0–23)

8 (0–15)

-5 (-9 to 19)

20

14 (2–30)

30 (0–50)

16 (8 to 26)

PABF, % (95% Cl)

10

60 (52–80)

80 (70–90)

20 (14 to 27)

15

50 (41–82)

67 (61–93)

17 (9 to 27)

20

57 (38–80)

69 (55–92)

12 (0 to 25)

  1. NA not applicable; NB net benefit; NRFP net reduction in false-positives; PABF percentage of avoided biomedical failures; percentage of avoided biopsies; TPR true-positive.
  2. rate. aP < 0.05 for the comparison of AUCs.