Figure 2
From: Immunophenotype and function of circulating myeloid derived suppressor cells in COVID-19 patients
Expression levels of intracellular TGF-β in MDSCs. The frequencies of TGF-β+ M-MDSCs (A) and TGF-β+ non-M-MDSCs (B) as the percentage of the CD11b+HLA-DR-/low cells in moderate (M) and severe (S) COVID-19 patients compared with healthy control subjects (HC). The effect of sex on the percentage of TGF-β+ M-MDSCs (C) and of TGF-β+ non-M-MDSCs (D) is also shown. (E) Frequency of TGF-β+ M-MDSCs compared to non-M-MDSCs in HC and COVID-19 patients (both M and S). All values are presented as the mean or median and 5–95% percentile and comparisons made between control and patient groups were performed using ANOVA or Kruskal–Wallis followed by a the Tukey’s or Dunn’s tests for normally distributed or non-normally distributed data respectively.*P < 0.01, **P < 0.001, ***P < 0.0001 and ****P < 0.0001. HC healthy control, M moderate, S severe.
