Figure 1

(a) Venn diagram showing the distribution of proteins of origin of the identified peptides by mass spectrometry at four time-points. T1 baseline (before placement of orthodontic appliance), T2 1 h after placement of orthodontic appliance, T3 1 week after placement of orthodontic appliance, T4 end of the alignment. (b) Heatmap displaying the percentages of peptides for the most abundant common proteins among all the participants (p1, p2, p3, p4, and p5) at four time-points. The scale refers to the percentages of peptides of each protein in the total number of peptides for each participant.