Figure 3

DAT binding. The estimates for the binding potentials were evaluated through the equilibrium ratios of the distribution areas of the specifically (striatum) and non-specifically (cerebellum) bound and striatal specific binding ratios (SBR_STR) for WT and Fmr1-^Δexon 8 rats. (A) [¹²³I]FP-CIT binding to striatal DAT in two WT adult rats. (B) [¹²³I]FP-CIT binding to striatal DAT in two Fmr1-^Δexon 8 adult rats. The striatal specific DAT binding ratio is shown in (C) (WT = 5; Fmr1-^Δexon 8 = 5). Data represents means ± SEM (Student’s t-test).