Figure 6 | Scientific Reports

Figure 6

From: Improved β-cell function leads to improved glucose tolerance in a transgenic mouse expressing lipoprotein lipase in adipocytes

Figure 6

SND1 promotes inflammatory gene expression in adipocytes. (A,B) Differentiated 3T3-L1 adipocytes were treated with control (scrambled) or Snd1 siRNA as indicated, and Snd11 mRNA expression and protein expression were determined. (C–F) Differentiated 3T3-L1 adipocytes were treated with control or Snd1 siRNA as indicated. Next, they were treated with 20 ng/mL TNFα for 6-h. The mRNA expression of (C) SND1, (D) CCL19, (E) IL6, and (F) MCP1 was determined with real time RT-PCR. The data are represented as the mean ± SEM (n = 3; *P < 0.05; **P < 0.01; ***P < 0.01; one way ANOVA with Tukey post hoc test); the data for SND1 is log transformed.

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