Table 1 ECHO MRI characterization of mice.

Parameter	Control	AdipoQ-LPL	P
All mice before the study^a
Weight (g)	26.4 ± 0.5	26.4 ± 0.3	0.90
Lean mass (g)	19.9 ± 0.4	19.3 ± 0.2	0.23
Fat mass (g)	2.8 ± 0.2	3.3 ± 0.2	0.04
Mice challenged with HFD^b
Weight (g)	27.8 ± 0.6	26.4 ± 0.5	0.06
Initial lean mass (g)	20.9 ± 0.5	19.6 ± 0.4	0.03
Final lean mass (g)	20.7 ± 0.5	19.5 ± 0.3	0.03
Delta lean mass (g)	−0.2 ± 0.3	−0.1 ± 0.2	0.70
Initial fat mass (g)	3.0 ± 0.3	3.2 ± 0.3	0.62
Final fat mass (g)	7.7 ± 0.5	7.4 ± 0.4	0.61
Delta fat mass	4.7 ± 0.3	4.2 ± 0.3	0.29
Mice maintained on chow^c
Initial weight (g)	25.2 ± 2	26.3 ± 1.6	0.13
Initial lean mass(g)	18.9 ± 1.5	19.1 ± 0.8	0.71
Final lean mass (g)	19.7 ± 1.3	19.6 ± 0.9	0.77
Delta lean mass (g)	0.8 ± 0.7	0.5 ± 0.5	0.20
Initial fat mass (g)	2.6 ± 0.5	3.5 ± 0.9	0.01
Final fat mass (g)	3.3 ± 0.8	4.6 ± 1.7	0.02
Delta fat mass (g)	0.7 ± 0.4	1.1 ± 0.9	0.12

^aAdipoQ-LPL transgenic male mice and their littermate controls (age 9–9.5 weeks) were characterized by ECHO-MRI before and after an acute high fat diet challenge in calorimetry chambers; a group of mice was maintained on chow as a control group. These data are for the entire cohort (control n = 25; AdipoQ-LPL n = 23) before the study. Data are represented as means ± standard error of the mean.
^bAdipoQ-LPL transgenic male mice and their littermate controls were characterized in a 1-week chow and 1-week high fat diet (60% cal fat) feeding study in calorimetry chambers (n = 12 control and n = 12 AdipoQ-LPL per group). Data are represented as means ± standard error of the mean.
^cAdipoQ-LPL transgenic male mice and their littermate controls were maintained on chow (n = 13 control and n = 11 AdipoQ-LPL per group). Data are represented as means ± standard error of the mean.

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