Table 3 Genes in the pancreatic β-cell gene set.

From: Improved β-cell function leads to improved glucose tolerance in a transgenic mouse expressing lipoprotein lipase in adipocytes

Gene symbola

Gene title

SYT13

Synaptotagmin XIII

MAFB

v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

INSM1

Insulinoma-associated 1

INS

Insulin

PCSK1

Proprotein convertase subtilisin/kexin type 1

NKX6-1

NK6 transcription factor related, locus 1 (Drosophila)

DCX

Doublecortex; lissencephaly, X-linked (doublecortin)

CHGA

Chromogranin A (parathyroid secretory protein 1)

NEUROD1

Neurogenic differentiation 1

SLC2A2

Solute carrier family 2 (facilitated glucose transporter), member 2

SCGN

Secretagogin, EF-hand calcium binding protein

SST

Somatostatin

G6PC2

Glucose-6-phosphatase, catalytic, 2

FOXA2

Forkhead box A2

AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

null

Null

GCK

Glucokinase (hexokinase 4, maturity onset diabetes of the young 2)

DPP4

Dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)

PCSK2

Proprotein convertase subtilisin/kexin type 2

PAX4

Paired box gene 4

ISL1

ISL1 transcription factor, LIM/homeodomain, (islet-1)

GCG

Glucagon

ABCC8

ATP-binding cassette, sub-family C (CFTR/MRP), member 8

null

Null

PAX6

Paired box gene 6 (aniridia, keratitis)

null

Null

NKX2-2

NK2 transcription factor related, locus 2 (Drosophila)

IAPP

Islet amyloid polypeptide

PAK3

p21 (CDKN1A)-activated kinase 3

VDR

Vitamin D (1,25-dihydroxyvitamin D3) receptor

NEUROG3

Neurogenin 3

SPCS1

Signal peptidase complex subunit 1 homolog (S. cerevisiae)

LMO2

LIM domain only 2 (rhombotin-like 1)

STXBP1

syntaxin binding protein 1

PKLR

Pyruvate kinase, liver and RBC

SRP9

Signal recognition particle 9 kDa

SRPRB

Signal recognition particle receptor, B subunit

  1. aThe gene symbols and gene titles of the GSEA pancreatic β-cell gene set are indicated.