Table 2 Changes in lipid levels (mean and SD) from the third month to each time point among patients with different endocrine therapies.

From: Comparison of changes in lipid profiles of premenopausal women with early-stage breast cancer treated with different endocrine therapies

 

TAM

OFS + TAM

OFS + AI

3 months

6 months

12 months

24 months

3 months

6 months

12 months

24 months

3 months

6 months

12 months

24 months

(baseline)

(baseline)

(baseline)

TC

4.60 ± 1.11

4.50 ± 1.00

4.53 ± 1.07

4.54 ± 1.01

4.55 ± 0.89

4.39 ± 0.80

4.45 ± 0.76

4.60 ± 0.86

4.88 ± 1.23

4.91 ± 0.88

5.10 ± 1.14

5.36 ± 1.15

(mmol/L)

 

P = 0.088

P = 0.194

P = 0.308

 

P = 0.171

P = 0.416

P = 0.560

 

P = 0.866

P = 0.226

P = 0.017

TG

1.88 ± 1.63

1.91 ± 1.34

1.89 ± 1.74

1.74 ± 1.54

2.10 ± 1.56

1.79 ± 0.74

1.88 ± 1.20

1.82 ± 0.76

1.32 ± 0.50

1.25 ± 0.57

1.29 ± 0.45

1.13 ± 0.35

(mmol/L)

 

P = 0.782

P = 0.971

P = 0.192

 

P = 0.091

P = 0.194

P = 0.105

 

P = 0.852

P = 0.927

P = 0.613

LDL-C

2.38 ± 0.92

2.25 ± 0.83

2.25 ± 0.88

2.19 ± 0.84

2.30 ± 0.71

2.22 ± 0.66

2.22 ± 0.62

2.23 ± 0.70

2.73 ± 0.89

2.88 ± 0.60

2.91 ± 0.81

3.01 ± 0.79

(mmol/L)

 

P = 0.004

P = 0.004

P < 0.001

 

P = 0.356

P = 0.342

P = 0.337

 

P = 0.319

P = 0.194

P = 0.067

HDL-C

1.38 ± 0.32

1.40 ± 0.34

1.43 ± 0.32

1.51 ± 0.34

1.42 ± 0.34

1.43 ± 0.31

1.47 ± 0.32

1.51 ± 0.30

1.35 ± 0.24

1.35 ± 0.29

1.41 ± 0.31

1.47 ± 0.24

(mmol/L)

 

P = 0.409

P = 0.018

P < 0.001

 

P = 0.767

P = 0.076

P = 0.015

 

P = 0.972

P = 0.360

P = 0.107

  1. P value correspond to baseline (treated with endocrine therapy for 3 months).
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