Table 2 Comparison of clinical characteristics between subjects without ligamentous ossification (control group) and those with OLF, C-OPLL, and T-OPLL.

From: Strong relationship between dyslipidemia and the ectopic ossification of the spinal ligaments

Variable

Control

(n = 230)

OLF

(n = 167)

C-OPLL

(n = 28)

T-OPLL

(n = 33)

Age (years)

50.2 ± 9.5

53.3 ± 10.5*

54.0 ± 9.6

55.2 ± 9.8*

BMI (kg/m2)

23.0 ± 3.3

24.2 ± 3.6*

26.1 ± 3.4*

27.3 ± 4.7*

Male (%)

43.0

64.6*

82.1*

63.6

Comorbidity (%)

Hypertension

14.3

22.1

30.7

33.3*

Diabetes mellitus

2.1

5.3

23.0*

6.0§

Ischemic heart disease

5.2

5.9

11.5

12.1

Stroke

1.7

1.7

3.8

0

Renal disease

0.4

0

0

0

Smoking (%)

50.8

58.0

53.8

57.5

Glucose during fasting (mg/dL)

98.3 ± 14.8

103.8 ± 22.9*

110.4 ± 27.1*

105.7 ± 15.5

HbA1c (%)

5.5 ± 0.4

5.7 ± 0.7

6.0 ± 1.0*

5.8 ± 0.5

Weight gain since age 20 years (%)

36.9

50.2*

69.2*

54.5

Exercise for at least 30 min per day (%)

18.2

18.5

11.5

18.1

T-Cho (mg/dL)

210.0 ± 36.5

208.1 ± 31.4

210.4 ± 36.2

204.2 ± 31.7

TG (mg/dL)

91.0 ± 52.8

108.4 ± 62.9*

143.6 ± 81.9*

121.4 ± 51.1*

HDL-C (mg/dL)

65.2 ± 16.0

60.9 ± 15.0*

55.2 ± 14.3*

55.3 ± 13.6*

LDL-C (mg/dL)

122.6 ± 33.3

125.6 ± 30.3

128.7 ± 34.6

126.4 ± 29.9

L/H ratio

2.0 ± 0.8

2.2 ± 0.8

2.4 ± 0.9

2.4 ± 0.9*

L/H ≤ 1.5 (%)

30.4

22.1

15.3

6.0*

L/H ≥ 2.0 (%)

46.0

56.2

69.2

63.6

L/H ≥ 2.5 (%)

25.6

34.1

50.0*

42.4

L/H ≥ 3.0 (%)

13.4

20.9

26.9

30.3

  1. Data are shown as mean ± SD or as percentage. L/H ratio represents LDL-C/HDL-C.
  2. (*P < 0.01 vs. control group).
  3. (P < 0.01 vs. OLF group).
  4. (§P < 0.01 vs. C-OPLL group).
  5. OPLL, ossification of the posterior longitudinal ligament; OLF, ossification of the ligamentum flavum; BMI, body mass index; T-Cho, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; C, cervical; T, thoracic.