Figure 2
From: Global lysine methylome profiling using systematically characterized affinity reagents
Pan-methyllysine antibodies exhibit sequence bias. Heatmaps depicting average fluorescent signal intensity (n = 3) from a microarray hybridized with the indicated commercially available antibody. Data is globally normalized to the highest signal on the microarray and the color code is proportional to the fluorescent signal, where red (1) indicates more antibody hybridization and blue (0) indicates less antibody hybridization. Rows show the identity of each fixed residue and columns show the position within the sequence relative to the central lysine residue (P0). The modification state of the central lysine residue is indicated by the title above each grouped heatmap.
