Figure 1 | Scientific Reports

Figure 1

From: A model for estimating the brainstem volume in normal healthy individuals and its application to diffuse axonal injury patients

Figure 1

Relationship between each ROI volume and age (a) or ICV (b) in 182 healthy subjects. (a) There were no significant correlations between regional volume and age for the whole brainstem (Pearson’s r = 0.093, P = 0.213), medulla (r = 0.029, P = 0.698), pons (r = 0.145, P = 0.050), or midbrain (r = 0.00046, P = 0.995), whereas a significant negative correlation was found for the cerebrum (r =  − 0.332, P = 4.77E-06). (b) There were significant positive correlations between regional volume and ICV (r = 0.496, 0.567, 0.677, 0.614, and 0.828 for the medulla, pons, midbrain, whole brainstem, and cerebrum, respectively; P < 1.0E-11). However, none of the ROI volumes showed direct proportionality to ICV, reflected by the positive y-intercepts of the regression lines on the scatterplot with ICV on the x-axis and each regional volume on the y-axis. *Significant at P < 0.05. ROI Region of interest, ICV Intracranial volume.

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