Figure 5 | Scientific Reports

Figure 5

From: Antiplasmodial activity, structure–activity relationship and studies on the action of novel benzimidazole derivatives

Figure 5The alternative text for this image may have been generated using AI.

Changes to mitochondrial membrane potential caused by antiplasmodial compounds. Fluorometry was used to measure the effects on the mitochondria of P. falciparum parasites caused by treatment with compounds that show activity against their growth in culture. A membrane disruptor (CCCP) was added as a positive control and untreated cultures were used as the negative one. All compounds were tested at 1 µM in triplicates, n = 3. (a) BZ 1, (b) BZ 5, (c) BZ 16, (d) BZ 26 and (e) BZ 33. *p < 0.05, **p < 0.01, ***p < 0.005.

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