Figure 5 | Scientific Reports

Figure 5

From: Subtle changes in perivascular endometrial mesenchymal stem cells after local endometrial injury in recurrent implantation failure

Figure 5

Altered decidualization capacity of SUSD2+ cells between first and second LEI. Confluent SUSD2+ cells adopt an epitheloid shape with prominent nucleoli and denser cytoplasm in the presence of MPA and 8-bromo-cAMP (a). Scale bar 100um. All 5 samples showed a reduction in Prolactin (b) and IGFBP1 (c) protein levels in the supernatant between first and second LEI. Relative expression of both PRL (Prolactin) and IGFBP1 mRNA by qPCR also showed marked reduction between (d). Data normalized to Prolactin and IGFBP1 levels of cells cultured in propagation medium. **p < 0.01.

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