Figure 1 | Scientific Reports

Figure 1

From: Nanosecond pulsed electric field suppresses growth and reduces multi-drug resistance effect in pancreatic cancer

Figure 1

The response of EPP85-181RDB, EPP85-181RNOV and EPP85-181P cell lines to nsPEF (8 kV/cm, 200 ns, 100 pulses, 10 kHz). The photographs were captured before, 1 min, 5 min and 13 min after pulse application. The top panel shows the ultrastructure of the cells obtained by the holotomography reconstruction and the bottom panel shows the fluorescence of Yo-Pro-1 after the administration of nsPEF, blue arrows—MVs release from the cell membrane, red arrows—YoPro-1 stain signal in the cells.

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