Figure 1

Change in alpha diversity and bacterial load by beta-lactam pharmacokinetic exposure from pulmonary exacerbation to end of antibiotic treatment. Panel (A) Change in Species Observed. Panel (B) Change in Shannon Diversity. Panel (C) Change in Inverse Simpson Index. Panel (D) Log Change in Bacterial Load. PK, pharmacokinetics; PEx, pulmonary exacerbation; E, pulmonary exacerbation; T, end of treatment; ET, change between pulmonary exacerbation and end of treatment. Plus signs represent the mean.