Table 1 Statistics of included participants. Data are presented as mean (SD) or n (%). For a histogram of the age distributions, we refer to Supplementary Fig. 1.
From: The necessity of incorporating non-genetic risk factors into polygenic risk score models
UKB | Lifelines | |
|---|---|---|
Number of included individuals | 406,159 | 36,130 |
Number of males | 186,493 (45.9%) | 15,004 (41.5%) |
Number of females | 219,666 (53.8%) | 21,126 (58.5%) |
Age range (years) | 38–75 | 5–91 |
Body mass index (BMI), kg/m2 | 27.4 (SD:4.8) | 25.0 (SD:4.6) |
Number of individuals currently smoking | 41,105 (10.12%) | 6,203 (17.2%) |
Number of individuals smoking in the past | 184,388 (45.4%) | 11,001 (30.4%) |
Average days/week with vigorous activity | 1.7 | 2.2 |
Average days/week with moderate activity | 3.4 | 4.2 |
T2D prevalence at first assessment | 20,118 (5.0%) | 547 (1.5%) |
T2D incidence after first assessment | 8363 (2.1%) | 270 (0.75%) |
CAD prevalence at first assessment | 13,648 (3.4%) | 516 (1.43%) |
CAD incidence after first assessment | 9027 (2.2%) | 255 (0.71%) |
