Figure 2 | Scientific Reports

Figure 2

From: Heating-mediated purification of active FGF21 and structure-based design of its variant with enhanced potency

Figure 2

Temperature-dependent CD spectra of the wild type FGF21. Far-UV CD spectra upon heating (A) and cooling (C), and near-UV CD spectra upon heating (B) and cooling (D). Profiles at different temperatures are represented using different colored lines as shown in the right box of the figure. Gray arrows indicate the directions of spectral changes during heating and cooling. (E) The molar ellipticity [θ] values as temperature increases and decreases are colored in red and blue, respectively. For this figure, [θ] of FGF21 at 225 nm was used since far-UV CD spectral changes were dramatic at this wavelength.

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