Table 2 Liver function test of experimental mice treated with high doses of 5B2T.
Groups | Total Billirubin (mg/dL) | Direct Billirubin (mg/dL) | Indirect Billirubin (mg/dL) | AST (U/L) | ALT (U/L) | ALP (U/L) |
|---|---|---|---|---|---|---|
Male mice | ||||||
Vehicle | 1.1 ± 0.8 | 0.1 ± 0.2 | 0.2 ± 0.3 | 25.4 ± 0.1 | 33.1 ± 0.3 | 100.5 ± 0.2 |
2 g/kg 5B2T | 1.0 ± 0.1 | 0.1 ± 0.2 | 0.3 ± 0.1 | 24.9 ± 0.1 | 34.1 ± 0.6 | 110.6 ± 0.1 |
5 g/kg 5B2T | 1.0 ± 0.2 | 0.2 ± 0.1 | 0.2 ± 0.2 | 25.0 ± 0.3 | 33.5 ± 0.9 | 109.3 ± 0.4 |
Female mice | ||||||
Vehicle | 1.2 ± 0.2 | 0.1 ± 0.3 | 0.2 ± 0.1 | 22.2 ± 1.1 | 36.3 ± 0.3 | 110.4 + 0.7 |
2 g/kg 5B2T | 1.2 ± 0.3 | 0.1 ± 0.1 | 0.2 ± 0.3 | 23.5 ± 0.8 | 36.0 ± 0.0 | 111.5 ± 0.3 |
5 /kg 5B2T | 1.2 ± 0.1 | 0.2 ± 0.3 | 0.2 ± 0.3 | 22.5 ± 0.6 | 36.1 ± 0.1 | 111.3 ± 0.3 |
