Table 2 Animal characteristics at 3 days postdenervation.
From: Angiotensin II type 1a receptor deficiency alleviates muscle atrophy after denervation
AT1a+/+-Cont (n = 9) | AT1a+/+-Den, 3 days (n = 9) | AT1a−/−-Cont (n = 9) | AT1a−/−-Den, 3 days (n = 10) | |
|---|---|---|---|---|
Body weight (g) pre-operation | 26.8 ± 0.63 | 26.4 ± 0.52 | 29.6 ± 1.06** | 30.3 ± 0.58## |
Body weight (g) pre-tissue harvest | 24.7 ± 0.55 | 24.9 ± 0.58 | 26.5 ± 0.92 | 27.3 ± 0.52# |
Grip strength (N) | 2.97 ± 0.1 | 2.87 ± 0.1 | 2.83 ± 0.11 | 2.89 ± 0.09 |
Grip strength (N)/body weight (kg) | 111.31 ± 3.96 | 108.6 ± 3.07 | 95.97 ± 3.35* | 95.44 ± 2.83# |
Skeletal muscles (mg) | ||||
Gastrocnemius | 136.26 ± 3.00 | 133.38 ± 2.49 | 128.51 ± 6.19 | 133.80 ± 1.92 |
Tibialis anterior | 49.58 ± 1.14 | 50.98 ± 1.00 | 49.97 ± 1.97 | 52.18 ± 0.57 |
Soleus | 7.96 ± 0.19 | 8.11 ± 0.22 | 7.68 ± 0.54 | 7.98 ± 0.16 |
Skeletal muscles (mg)/body weight (g) | ||||
Gastrocnemius | 5.52 ± 0.074 | 5.36 ± 0.068 | 4.83 ± 0.086** | 4.91 ± 0.093## |
Tibialis anterior | 2.01 ± 0.022 | 2.05 ± 0.029 | 1.88 ± 0.022** | 1.92 ± 0.034## |
Soleus | 0.32 ± 0.0069 | 0.33 ± 0.0067 | 0.29 ± 0.012** | 0.29 ± 0.0046## |