Table 2 Animal characteristics at 3 days postdenervation.

From: Angiotensin II type 1a receptor deficiency alleviates muscle atrophy after denervation

 

AT1a+/+-Cont (n = 9)

AT1a+/+-Den, 3 days (n = 9)

AT1a−/−-Cont (n = 9)

AT1a−/−-Den, 3 days (n = 10)

Body weight (g) pre-operation

26.8 ± 0.63

26.4 ± 0.52

29.6 ± 1.06**

30.3 ± 0.58##

Body weight (g) pre-tissue harvest

24.7 ± 0.55

24.9 ± 0.58

26.5 ± 0.92

27.3 ± 0.52#

Grip strength (N)

2.97 ± 0.1

2.87 ± 0.1

2.83 ± 0.11

2.89 ± 0.09

Grip strength (N)/body weight (kg)

111.31 ± 3.96

108.6 ± 3.07

95.97 ± 3.35*

95.44 ± 2.83#

Skeletal muscles (mg)

 Gastrocnemius

136.26 ± 3.00

133.38 ± 2.49

128.51 ± 6.19

133.80 ± 1.92

 Tibialis anterior

49.58 ± 1.14

50.98 ± 1.00

49.97 ± 1.97

52.18 ± 0.57

 Soleus

7.96 ± 0.19

8.11 ± 0.22

7.68 ± 0.54

7.98 ± 0.16

Skeletal muscles (mg)/body weight (g)

 Gastrocnemius

5.52 ± 0.074

5.36 ± 0.068

4.83 ± 0.086**

4.91 ± 0.093##

 Tibialis anterior

2.01 ± 0.022

2.05 ± 0.029

1.88 ± 0.022**

1.92 ± 0.034##

 Soleus

0.32 ± 0.0069

0.33 ± 0.0067

0.29 ± 0.012**

0.29 ± 0.0046##

  1. Values are means ± SE. *P < 0.05 and **P < 0.01 vs AT1a+/+-Cont; #P < 0.05 and ##P < 0.01 vs AT1a+/+-Den (3 days).