Table 1 Clinical parameters of 277 study subjects.

From: Microdeletions and microduplications linked to severe congenital disorders in infertile men

Parametera

Non-obstructive azoospermia (NOA)

Severe oligozoospermia (SO)

Moderate oligozoospermia (MO)

Normozoospermic fertile men (NORM)b

Subgroup size (n)

73

84

58

62

Age (years)

33.7 (21.6–58.0)

35.6 (18.1–55.4)

32.4 (20.0–57.8)

31.0 (22.0–53.0)

Height (cm)

180 (169–197)

178 (166–198)

181.5 (162–210)

180 (171–193)

Weight (kg)

85.9 (54.3–127.7)

85.2 (55.7–125.8)

86.2 (59.7–123.0)

80.3 (62.0–107.4)

BMI (kg/m2)

26.1 (18.7–35.7)

26.9 (18.4–37.8)

25.7 (18.0–34.4)

25.0 (19.7–34.2)

Total testis volume (ml)

27 (7–49)

28 (7–55)

28 (18–56)

47.5 (34–100)

Semen volume (ml)

3.4 (0.5–8.9)

3.6 (0.6–8.2)

4.0 (1.4–9)

4.1 (1.8–9.4)

Total sperm count (× 106/ ejaculate)

0 (0–0)

2.4 (0.004–9.9)

21.3 (10–37.8)

430.3 (49.5–1540)

Sperm concentration (× 106/ml)

0 (0–0)

0.9 (0.001–14)

5.0 (1.8–19)

115 (15–355)

Progressive A + B motility (%)c

n/a

14.5 (0–70)

30 (0–60)

55 (41–84)

Sperm with normal morphology (%)d

n/a

0 (0–12)

2 (0–12)

14 (2–27)e

FSH (IU/l)

24.9 (4.8–70.5)

17.4 (2.7–41.1)

13.4 (4.1–30.5)

3.2 (0.8–6.8)

LH (IU/l)

8.3 (2.7–27.8)

5.9 (2.2–16.4)

4.8 (2.5–14.6)

3.4 (1.5–6.8)

Total testosterone (nmol/l)

14.0 (1.0–45.0)

16.5 (3.5–46.0)

16.5 (5.8–41.1)

16.7 (9.1–30.1)

  1. aMedian (range) is shown for each parameter.
  2. bNormozoospermic (total sperm count > 39 × 106/ ejaculate) partners of pregnant women.
  3. cWHO normal range 30–75%14.
  4. dWHO normal range 4–39%14.
  5. e61/62 subjects in the NORM subgroup had normal sperm morphology (10–27% of sperm).
  6. n/a, not applicable.