Figure 3 | Scientific Reports

Figure 3

From: The renin-angiotensin system modulates endotoxic postconditioning of exacerbated renal vasoconstriction in preeclamptic offspring

Figure 3

Effect of PE programming on the cumulative vasoconstrictor response curves of phenylephrine (A) and AUCs of the phenylephrine cumulative vasoconstrictor response curves (B) measured 4 h post LPS challenge (5 mg/kg) in isolated perfused kidneys of adult male offspring. The influence of prenatal administration of Ang1-7 is also shown. Contractile responses were estimated as changes from basal renal perfusion pressure. Values are expressed as means ± S.E.M of 7–8 measurements. ANOVA followed by the Tukey's post hoc was utilized to measure statistical significance. +P < 0.05 vs. “PE”, #P < 0.05 vs. “PE/LPS” in the same sex.

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