Table 1 Neonatal & maternal socio-demographic factors of study population (N; %, the dominator number is indicated when there is missing data).

From: Prevalence, predictors, and outcomes of major congenital anomalies: A population-based register study

Risk factors and outcomes

Any congenital anomaly

P-value

Yes (n = 332)

n (%)

No (n = 24,741)

n (%)

Total (n = 25,073)

n (%)

Nationality

0.102

 Qatari

93 (28)

5770/24,737 (23.3)

5863/25,069 (23.4)

 

 Other arabs

138 (41.6)

10,483/24,737 (42.4)

10,621/25,069 (42.4)

 

 Other nationalities

101 (30.4)

8484/24,737 (34.3)

8585/25,069 (34.2)

 

Maternal age

0.185

 20–34 years

250 (75.3)

19,579 (79.1)

19,829 (79.1)

 

 < 20 years

6 (1.8)

482 (1.9)

488 (1.9)

 

 ≥ 35 years

76 (22.9)

4680 (18.9)

4756 (19)

 

Pregnancy type

0.000

 Singleton

297 (89.5)

23,739 (96)

24,036 (95.9)

 

 Multiple

35 (10.5)

1002 (4)

1037 (4.1)

 

Parity

0.491

 Nulliparous

100 (30.1)

7026/24,737 (28.4)

7126/25,069 (28.4)

 

 Parity ≥ 1

232 (69.9)

17,711/24,737 (71.6)

17,943/25,069 (71.6)

 

Diabetes

0.017

 None

234 (70.5)

17,170 (69.4)

17,404/18,693 (69.4)

 

 GDM

83 (25)

7000 (28.3)

7083/18,693 (28.2)

 

 PGDM

15 (4.5)

571 (2.3)

586/18,693 (2.3)

 

Chronic hypertension

0.978

 No

328 (98.8)

24,447 (98.8)

24,775 (98.8)

 

 Yes

4 (1.2)

294 (1.2)

298 (1.2)

 

Consanguinity

0.115

 No

65/104 (62.5)

5832/8372 (69.7)

5897/8476 (69.6)

 

 Yes

39/104 (37.5)

2540/8372 (30.3)

2579/8476 (30.4)

 

Pregnancy mode

0.000

 Spontaneous

299/330 (90.6)

23,688/24,603 (96.3)

23,987/24,933 (96.2)

 

 Assisted conception

31/330 (9.4)

915/24,603 (3.7)

946/24,933 (3.8)

 

Delivery mode

0.000

 Vaginal

170 (51.2)

16,347 (66.1)

16,517 (65.9)

 

 Caesarean

162 (48.8)

8394 (33.9)

8556 (34.1)

 

Gestational age at birth

0.000

 24–31 weeks

43 (13)

376 (1.5)

419 (1.7)

 

 32–36 weeks

73 (22)

2028 (8.2)

2101 (8.4)

 

 ≥ 37 weeks

216 (65.1)

22,337 (90.3)

22,553 (89.9)

 

Birth weight

0.000

 ≤ 2499 g

124/331 (37.5)

2276/24,733 (9.2)

2400/25,064 (9.6)

 

 ≥ 2500 g

207/331 (62.5)

22,457/24,733 (90.8)

22,664/25,064 (90.4)

 

Macrosomic baby

0.073

 < 4 kg

322/331 (97.3)

23,536/24,733 (95.2)

23,858/25,064 (95.2)

 

 ≥ 4 kg

9/331 (2.7)

1197/24,733 (4.8)

1206/25,064 (4.8)

 

Apgar < 7 at 1 min

0.000

 No

270 (81.3)

24,168 (97.7)

24,438 (97.5)

 

 Yes

62 (18.7)

573 (2.3)

635 (2.5)

 

Apgar < 7 at 5 min

0.000

 No

309 (93.1)

24,686 (99.8)

24,995 (99.7)

 

 Yes

23 (6.9)

55 (0.2)

78 (0.3)

 

Gender

0.294

 Male

179 (53.9)

12,619/24,735 (51)

12,798/25,067 (51.1)

 

 Female

153 (46.1)

12,116/24,735 (49)

12,269/25,067 (48.9)

 

Baby outcome

0.000

 Discharged alive

281 (84.6)

24,693/24,739 (99.8)

24,974/25,071 (99.6)

 

 Died in hospital

51 (15.4)

46/24,739 (0.2)

97/25,071 (0.4)

 

Baby disposition

0.000

 Postnatal ward

46 (13.9)

21,056 (85.1)

21,102 (84.2)

 

 NICU or died in LR/OT

286 (86.1)

3682 (14.9)

3968 (15.8)

 

Maternal BMI

0.164

 Normal

37/128 (28.9)

3282/9606 (34.2)

3319/9734 (34.1)

 

 Underweight

7/128 (5.5)

250/9606 (2.6)

257/9734 (2.6)

 

 Overweight

43/128 (33.6)

3171/9606 (33)

3214/9734 (33)

 

 Obese

41/128 (32)

2903/9606 (30.2)

2944/9734 (30.2)

 
  1. GDM gestational diabetes mellitus, PGDM pregestational diabetes mellitus.
  2. Missing data for: nationality (n = 4), parity (n = 4), consanguinity (n = 16,597), maternal BMI (15,339), pregnancy mode (n = 140), birth weight/macrosomia (n = 9), gender (n = 4), baby outcome (n = 2).
  3. Significant values are in bold.