Table 3 Comparison of the performance of the current catalyst with several other catalysts in synthesis 2-amino-4,6-diphenylnicotinonitrile derivatives.

From: Synthesis, properties, and application of the new nanocatalyst of double layer hydroxides in the one-pot multicomponent synthesis of 2-amino-3-cyanopyridine derivatives

Entry

Reaction conditions

Time (min)

Yield (%)

Lit

1

Yb(PFO)3 (2.5 mol%), EtOH, reflux

240

90

35

2

Nano Fe3O4 (30 mg), solvent‐free, 80 °C

120

90

26

3

CoFe2O4@TRIS@ sulfated boric acid (5 mg), Solvent-free, 90 °C

35

90

21

4

Cu@imineZCMNPs, solvent-free, 80 °C

18

92

17

5

Bu4N+Br (10 mol%), H2O, reflux

120

92

18

6

GO (10), H2O, 80 °C

350

96

36

7

Fe3O4@TiO2@O2PO2(CH2)NHSO3H, solvent‐free, 90 °C

20

90

29

8

Mn@PMO-IL nanocatalyst, solvent free, 80 °C

15–100

55–95

37

9

Cellulose–SO3H (0.05 mmol), water, 60 °C

150

96

38

10

LDH@TRMS@NH2SO2(C2H4)SO2NH2@nano copper, solvent‐free, 60 °C

8

92

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