Figure 2 | Scientific Reports

Figure 2

From: TLR4 and MD2 variation among horses with differential TNFα baseline concentrations and response to intravenous lipopolysaccharide infusion

Figure 2

Construction of Equine TLR4-MD2-LP structure. (a) Structure of the human TLR4-MD2-LPS complex (PDB ID 3FXI)19, with TLR4 proteins (cyan blue), MD2 proteins (green), and LPS endotoxin (orange). (b) Merged equine (magenta) and human (cyan blue) TLR4 subunit, and merged equine (cornflower blue) and human (green) MD2 protein; LPS endotoxin (orange). (c) The complete structure of the equine TLR4-MD2-LPS complex, with TLR4 (sky blue), MD2 (magenta), and LPS endotoxin (orange).

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