Figure 7 | Scientific Reports

Figure 7

From: Microevolutionary dynamics of eccDNA in Chinese hamster ovary cells grown in fed-batch cultures under control and lactate-stressed conditions

Figure 7

Example of transcripts with regions containing SNPs that may have originated from an eccDNA template on chromosome 9 at base 14,641,267. Rows from top to bottom are: location of the sequence, coverage of the CHO-K1 reference assembly, the CHO-K1 reference genome, consensus eccDNA sequence for the Lactate-stressed Day 12 samples, coverage of the RNA data, RNA transcripts for the Lactate-stressed Day 12 cultures, and the Chinese hamster PICRH reference genome. The height of the gray bars in the coverage row reflects the amount of coverage for each nucleotide. Colored bars in the coverage row reflect SNPs relative to the reference genome. Nucleotides are shown as: adenine (A)—green, thymine (T)—red, guanine (G)—orange, and cytosine (C)—blue.

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