Table 3 Lipid-lowering therapy and adherence (medication possession ratio) by sex and age.

From: Women with familial hypercholesterolemia phenotype are undertreated and poorly controlled compared to men

Age (years)

LLT

Women, %

Men, %

P-value

8–14

Low-moderate potency

11.8 (14.7%)

10.4 (13.1%)

0.940

High-very high potency

1.7 (2.1%)

1.0 (1.3%)

Without LLT

67.0 (83.2%)

68.0 (85.6%)

MPR

38.8% (35.4%)

50.9% (32.2%)

0.444

15–24

Low-moderate potency

26.5 (23.0%)

17.4 (19.0%)

0.558

High-very high potency

5.7 (4.9%)

8.3 (9.1%)

Without LLT

83.0 (72.0%)

66.0 (72.0%)

MPR

49.5% (28.8%)

47.1% (28.4%)

0.681

25–34

Low-moderate potency

60.1 (29.9%)

76.5 (30.7%)

0.848

High-very high potency

24.2 (12.0%)

34.8 (14.0%)

Without LLT

117.0 (58.1%)

138.0 (55.4%)

MPR

54.5% (26.9%)

49.9% (27.4%)

0.302

35–44

Low-moderate potency

148.4 (37.9%)

381.5 (46.0%)

0.005

High-very high potency

53.9 (13.8%)

132.1 (15.9%)

Without LLT

189.0 (48.3%)

315.0 (38.0%)

MPR

57.6% (27.7%)

55.4% (27.8%)

0.420

45–54

Low-moderate potency

498.8 (61.2%)

688.3 (57.0%)

0.058

High-very high potency

165.6 (20.3%)

307.3 (25.5%)

Without LLT

151.0 (18.5%)

211.0 (17.5%)

MPR

61.1% (28.1%)

64.9% (27.6%)

0.068

55–64

Low-moderate potency

1417.0 (68.9%)

1091.6 (63.8%)

0.000

High-very high potency

426.8 (20.8%)

495.0 (28.9%)

Without LLT

213.0 (10.4%)

124.0 (7.2%)

MPR

66.5% (27.5%)

71.7% (26.8%)

0.000

65–74

Low-moderate potency

1705.3 (74.5%)

1022.7 (63.3%)

0.000

High-very high potency

488.2 (21.3%)

544.7 (33.7%)

Without LLT

96.0 (4.2%)

49.0 (3.0%)

MPR

73.0% (26.2%)

78.4% (24.1%)

0.000

75–84

Low-moderate potency

1121.6 (75.0%)

520.1 (65.6%)

0.002

High-very high potency

328.0 (21.9%)

250.6 (31.6%)

Without LLT

45.0 (3.0%)

22.0 (2.8%)

MPR

76.0% (24.7%)

80.0% (23.1%)

0.033

85 + 

Low-moderate potency

384.3 (77.8%)

103.8 (69.4%)

0.139

High-very high potency

86.5 (17.5%)

42.7 (28.6%)

Without LLT

23.0 (4.7%)

3.0 (2.0%)

MPR

73.5% (26.5%)

77.5% (24.9%)

0.362

  1. LLT Lipid lowering therapy, MPR medication possession ratio, LDL-C low-density lipoprotein cholesterol.