Table 2 Top transcriptional activation (upregulated) and repression (downregulated) responses of human monocytes infected with GBS.
ENSEMBL ID* | Label | Gene product | FC | P-adj |
|---|---|---|---|---|
00000169245.6 | CXCL10 | C-X-C motif chemokine ligand 10 | 117.7 | 7.4E − 43 |
00000169429.11 | CXCL8 | C-X-C motif chemokine ligand 8 | 94.4 | 2.4E − 49 |
00000243455.3 | RPS18P13 | Ribosomal protein S18 pseudogene 13 | 89.7 | 6.2E − 08 |
00000123610.5 | TNFAIP6 | TNF alpha induced protein 6 | 61.8 | 1.3E − 09 |
00000270390.1 | SFXN4P1 | SFXN4 pseudogene 1 | 48.5 | 5.6E − 11 |
00000225286.1 | Ribosomal protein S2 (RPS2) pseudogene | 44.3 | 2.0E − 04 | |
00000118503.15 | TNFAIP3 | TNF alpha induced protein 3 | 42.1 | 2.9E − 225 |
00000115009.13 | CCL20 | C–C motif chemokine ligand 20 | 36.4 | 3.7E − 28 |
00000138670.17 | RASGEF1B | RasGEF domain family member 1B | 33.5 | 2.7E − 07 |
00000090104.12 | RGS1 | Regulator of G protein signaling 1 | 33.3 | 5.3E − 51 |
00000250033.5 | SLC7A11-AS1 | SLC7A11 antisense RNA 1 | 26.9 | 2.5E − 47 |
00000224969.1 | Novel transcript | 25.4 | 8.7E − 03 | |
00000269540.1 | Novel zinc finger protein pseudogene | 22.9 | 7.0E − 04 | |
00000163734.4 | CXCL3 | C-X-C motif chemokine ligand 3 | 22.5 | 9.3E − 04 |
00000235763.1 | SNRPGP5 | Small nuclear ribonucleoprotein polypeptide G# 5 | 21.3 | 1.9E − 02 |
00000173237.4 | C11orf86 | Chromosome 11 open reading frame 86 | 19.9 | 7.2E − 03 |
00000168367.11 | LINC00917 | Long intergenic non-protein coding RNA 917 | 19.6 | 7.6E − 03 |
00000198576.4 | ARC | Activity regulated cytoskeleton associated | 19.6 | 2.8E − 02 |
00000262400.1 | Calcium activated nucleotidase 1 (CANT1)# | 17.7 | 4.2E − 02 | |
00000081041.9 | CXCL2 | C-X-C motif chemokine ligand 2 | 16.7 | 6.7E − 36 |
00000196664.5 | TLR7 | Toll like receptor 7 | 16.6 | 1.1E − 03 |
00000105246.6 | EBI3 | Epstein-Barr virus induced 3 | 16.0 | 1.0E − 10 |
00000265237.1 | MIR3142 | microRNA 3142 | 16.0 | 2.0E − 02 |
00000260542.1 | Novel transcript | 15.7 | 7.6E − 04 | |
00000196611.5 | MMP1 | Matrix metallopeptidase 1 | 15.3 | 6.2E − 17 |
00000286274.1 | Novel transcript | − 46.3 | 6.6E − 03 | |
00000229204.3 | PTGES3P3 | Prostaglandin E synthase 3 pseudogene 3 | − 46.5 | 5.1E − 03 |
00000185155.11 | MIXL1 | Mix paired-like homeobox | − 46.7 | 1.0E − 04 |
00000238205.3 | MPC1L | Mitochondrial pyruvate carrier 1 like | − 47.0 | 1.1E − 02 |
00000271379.1 | Family with sequence similarity 173, member B# | − 47.7 | 6.9E − 04 | |
00000196562.14 | SULF2 | Sulfatase 2 | − 48.9 | 2.4E − 12 |
00000163106.11 | HPGDS | Hematopoietic prostaglandin D synthase | − 49.0 | 4.5E − 03 |
00000270811.1 | Ribosomal protein L21 (RPL21) pseudogene | − 49.1 | 8.9E − 03 | |
00000173250.2 | GPR151 | G protein-coupled receptor 151 | − 51.7 | 1.8E − 14 |
00000263096.1 | Novel transcript, antisense to HLF | − 52.0 | 2.5E − 03 | |
00000257065.1 | Novel protein | − 53.5 | 2.6E − 03 | |
00000223882.1 | ABCC5-AS1 | ABCC5 antisense RNA 1 | − 54.5 | 2.7E − 05 |
00000259362.2 | Novel transcript | − 55.3 | 2.5E − 03 | |
00000214070.3 | MANEALP1 | MANEAL pseudogene 1 | − 55.3 | 2.2E − 03 |
00000223375.1 | Ribosomal protein S26 (RPS26) pseudogenes | − 55.6 | 4.5E − 03 | |
00000269681.1 | CEACAM18#^ | − 60.8 | 1.1E − 03 | |
00000281048.2 | Novel transcript, antisense to PROP1 | − 60.8 | 1.1E − 03 | |
00000146477.6 | SLC22A3 | Solute carrier family 22 member 3 | − 62.3 | 7.8E − 04 |
00000118491.10 | ZC2HC1B | Zinc finger C2HC-type containing 1B | − 64.3 | 5.6E − 05 |
00000138075.14 | ABCG5 | ATP binding cassette subfamily G member 5 | − 67.3 | 4.4E − 04 |
00000273113.1 | Novel transcript | − 69.0 | 3.9E − 04 | |
00000271414.1 | MYC associated factor X, pseudogene | − 89.3 | 3.3E − 06 | |
00000255693.3 | LINC02389 | Long intergenic non-protein coding RNA 2389 | − 98.2 | 8.3E − 07 |
00000163032.12 | VSNL1 | Visinin like 1 | − 117.8 | 2.2E − 07 |
00000277518.3 | MUC6 | Mucin 6, oligomeric mucus/gel-forming | − 158.4 | 1.1E − 07 |
