Figure 3

Differential protein abundance in the amniotic fluid with and without labor at term. (a) Volcano plot showing log10-transformed false discovery rate adjusted p-values (q-values) against log2-transformed fold changes of the 1310 amniotic fluid proteins. (b) Heatmap based on proteins with significantly altered abundance (q<0.05 and fold change ≥ 1.5) between term not in labor (TNL, indicated by blue headers) and term in labor (TIL, indicated by red headers) samples. The R/Bioconductor packages, EnhancedVolcano157 and pheatmap158, were used to generate the volcano plot and heatmap, respectively.