Table 1 Clinical features of the patients with CRC in each cohort.
Variables | Training cohort (n = 253) | Test cohort (n = 253) | P | Entire TCGA cohort (n = 506) |
|---|---|---|---|---|
Age (years) | ||||
≤ 65 | 120 | 105 | 0.2104 | 225 |
> 65 | 133 | 148 | 281 | |
Gender | ||||
Female | 105 | 125 | 0.0898 | 230 |
Male | 148 | 128 | 276 | |
Survival status | ||||
Alive | 209 | 206 | 0.8169 | 415 |
Dead | 44 | 47 | 91 | |
Tumor invasion (T) | ||||
T1 | 7 | 8 | 0.9783 | 15 |
T2 | 45 | 46 | 91 | |
T3 | 174 | 170 | 344 | |
T4 | 27 | 29 | 56 | |
Lymph node (N) | ||||
N0 | 150 | 145 | 0.7674 | 295 |
N1 | 63 | 61 | 124 | |
N2 | 40 | 46 | 86 | |
Unknown | 0 | 1 | 1 | |
Metastasis (M) | ||||
M0 | 212 | 212 | 0.5926 | 424 |
M1 | 38 | 35 | 73 | |
Unknown | 3 | 6 | 9 | |
Tumor stage | ||||
Stage I | 44 | 47 | 0.6873 | 91 |
Stage II | 101 | 90 | 191 | |
Stage III | 67 | 75 | 142 | |
Stage IV | 38 | 35 | 73 | |
Unknown | 3 | 6 | 9 | |
Microsatellite instability | ||||
MSS | 168 | 170 | 0.5302 | 338 |
MSI-L | 41 | 43 | 84 | |
MSI-H | 36 | 37 | 73 | |
Unknown | 8 | 3 | 11 | |
Histological type | ||||
Adenocarcinoma | 217 | 222 | 0.3081 | 439 |
Mucinous adenocarcinoma | 31 | 30 | 61 | |
Unknown | 5 | 1 | 6 | |
Venous invasion | ||||
Yes | 60 | 50 | 0.5593 | 110 |
No | 158 | 166 | 324 | |
Unknown | 35 | 37 | 72 | |
