Figure 3 | Scientific Reports

Figure 3

From: Assessment of the therapeutic role of mesenchymal stromal cells in a mouse model of graft-versus-host disease using cryo-imaging

Figure 3

hMSCs were substantially found in the spleen which is the largest secondary lymphoid organ. Detected hMSCs were rendered in golden yellow (pseudo-color) in the spleen volume rendering (a). Fluorescent images show that red, Qdot-labeled, MSCs (arrow heads) were found to home specifically to the marginal zone (b, e) which is the interface between the red pulp (RP) and the white pulp (WP) (Subpanels c, f and movies in supplemental media 2–3). 3D visualizations of white pulp (blue surface renderings in d and g) show that there were more hMSCs in the spleen of the allogeneic group than in the spleen of the syngeneic group.

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